Page 1 of 2 12 LastLast
Results 1 to 25 of 26

Thread: Mo' Stuff about Castor Oil and Dry Eyes

  1. #1
    Banned
    Join Date
    Jun 2000
    Location
    Only City in the World built over a Volcano
    Occupation
    Dispensing Optician
    Posts
    12,996

    Mo' Stuff about Castor Oil and Dry Eyes

    Just for OrangeZero
    Cornea. 2007 Feb;26(2):175-81.
    Links


    Effect of an oil-in-water emulsion on the tear physiology of patients with mild to moderate dry eye.


    Khanal S, Tomlinson A, Pearce EI, Simmons PA.
    Department of Vision Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.
    PURPOSE: To determine the effect of an oil-in-water emulsion eye drop compared with a conventional dry eye supplement (hypromellose) on tear physiology in dry eye. METHODS: A randomized parallel, longitudinal, and investigator-masked study of the efficacy of 1.25% castor oil emulsion and 0.32% hypromellose solution was carried out. A total of 53 patients with mild to moderate dry eye (27 in emulsion group and 26 in hypromellose group) were recruited for the study. Patients were enrolled if they reported at least 2 symptoms on a McMonnies Dry Eye Questionnaire together with 1 of the following screening tests: noninvasive tear breakup time (5-10 seconds) and Schirmer test without anesthesia (2-5 mm in 5 minutes). Patients were instructed to use the test solutions 3 times a day for 30 days. Tear production, evaporation, lipid layer structure, and osmolality were measured before and 30 days after use of the drops. RESULTS: A statistically significant decrease was seen after 1 month in tear evaporation rates with both emulsion (7.25 +/- 5.43 g/m2/h) and hypromellose (2.02 +/- 4.75 g/m2/h). However, the decrease with emulsion was significantly greater than with hypromellose (P < 0.001). Lipid layer structure improved from day 1 to day 30 of the study with the emulsion but not with the hypermellose. No significant changes were seen in tear production and osmolality with either of the drops. CONCLUSIONS: The oil-water emulsion was more effective in reducing tear evaporation than hypromellose after repeated application over a 1-month period. This finding signifies the potential of the emulsion in the management of evaporative dry eye.

    Ophthalmology. 2002 Nov;109(11):2030-5.
    Links

    Low-concentration homogenized castor oil eye drops for noninflamed obstructive meibomian gland dysfunction.
    Goto E, Shimazaki J, Monden Y, Takano Y, Yagi Y, Shimmura S, Tsubota K.
    Department of Ophthalmology, Tokyo Dental College, Chiba, Japan.
    OBJECTIVE: We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. DESIGN: Randomized, double-masked, placebo-controlled crossover clinical trial. PARTICIPANTS: Forty eyes of 20 patients with noninflamed MGD. METHODS: After a preliminary study of eye drops containing castor oil, 2% castor oil and 5% polyoxyethylene castor oil (emulsifier) were mixed to formulate homogenized oil eye drops. The patients were assigned randomly to receive oil eye drops or placebo six times daily for 2 periods of 2 weeks each. MAIN OUTCOME MEASURES: At the end of each treatment period, we assessed symptoms, tear interference grade, tear evaporation, fluorescein and rose bengal scores, tear break-up time (BUT), and meibomian gland orifice obstruction. Safety and stability tests were also performed. RESULTS: Symptom scores, tear interference grade, tear evaporation test results, rose bengal scores, tear BUT, and orifice obstruction scores after the oil eye drop period showed significant improvement compared with the results after the placebo period. No complications attributable to the eye drops were observed. The oil eye drops were stable when stored at 4 degrees C. CONCLUSIONS: The results indicate that castor oil eye drops are effective and safe in the treatment of MGD. The possible mechanisms of this treatment are improvement of tear stability as a result of lipid spreading, ease of meibum expression, prevention of tear evaporation, and the lubricating effect of the oil eye drops.

    Girard LJ.


  2. #2
    Underemployed Genius Jacqui's Avatar
    Join Date
    Oct 2003
    Location
    Frostbite Falls, Mn.
    Occupation
    Optical Wholesale Lab (other positions)
    Posts
    7,417
    hmmm........ Grandmothers have known about that for years.
    Proud Member of the ABE Club!
    Don't feed the Beast...

  3. #3
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Redhot Jumper

    Good show Chip, we had a lively discussion on that subject a few years ago..........................

    There are thousands of applications for the stuff from inducing labor, emptying your bowels to treating eyes. Just had to buy another 42 gallon barrel this week for a few thousand dollars. So if you want to dispense any I have it in stock. :bbg:
    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  4. #4
    Master OptiBoarder OptiBoard Silver Supporter Now I See's Avatar
    Join Date
    Jan 2008
    Location
    free-n-clear!
    Occupation
    Dispensing Optician
    Posts
    1,864
    Thanks, Chip...

    That was an interesting read...I've got dry eyes, have plugs in my lower
    lids and still have trouble, mostly at night...my lids "stick" to my cornea, so I end up with corneal abrasions...doc had me try a night-time ointment...not sure I like it...my eyes feel better at night, but during the day they feel extra sensitive....

    Whoa..lots more info than any of you probably want to know about me..:hammer:..the point is, I appreciate the article. :D
    ___________________________________________

  5. #5
    Master OptiBoarder
    Join Date
    Oct 2004
    Location
    Down in a hole!
    Occupation
    Dispensing Optician
    Posts
    13,045
    Quote Originally Posted by Chris Ryser View Post
    There are thousands of applications for the stuff from inducing labor, emptying your bowels to treating eyes. Just had to buy another 42 gallon barrel this week for a few thousand dollars. So if you want to dispense any I have it in stock. :bbg:


    Holy Mackerel!

    I use a bit of castor oil in my home made muzzleloader "lubricants".

    Gotta love a little Moose Milk and Moose Snot combined with the smell of burnt black powder!!!

    ;):cheers::D:cheers:

  6. #6
    Master OptiBoarder optigrrl's Avatar
    Join Date
    Feb 2005
    Location
    The surface of the sun on a rainy day
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    1,336
    Quote Originally Posted by Chris Ryser View Post

    There are thousands of applications for the stuff from inducing labor, emptying your bowels to treating eyes. Just had to buy another 42 gallon barrel this week for a few thousand dollars. So if you want to dispense any I have it in stock. :bbg:
    Wonder what the shelf-life is for that stuff, better sell it fast!

  7. #7
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Big Smile Shake it ...........................

    Quote Originally Posted by optigrrl View Post
    Wonder what the shelf-life is for that stuff, better sell it fast!
    ...................... a few years is good enough, if you empty the stuff into 1 gallon glass bottles. It starts separating after a while abd you can see different layers. Heat it up in a warm water bath and shake back into solution and it is like new.
    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  8. #8
    Banned
    Join Date
    Jun 2000
    Location
    Only City in the World built over a Volcano
    Occupation
    Dispensing Optician
    Posts
    12,996
    Wouldn't heat it too hot, it clots when it cools. Sometimes it is used for a lubricant for racing engines (it's wonderful) but one has to drain from engine before the engine cools.
    Also supspect it is the main ingredient in 2 cycle oil, hense the need to burn the fuel to empty from engine.

    Chip

  9. #9
    Master OptiBoarder rbaker's Avatar
    Join Date
    May 2000
    Location
    Jacksonville, OR
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    4,297
    Quote Originally Posted by chip anderson View Post
    Wouldn't heat it too hot, it clots when it cools. Sometimes it is used for a lubricant for racing engines (it's wonderful) but one has to drain from engine before the engine cools.
    Also supspect it is the main ingredient in 2 cycle oil, hense the need to burn the fuel to empty from engine.

    Chip
    Castor oil was the lubricant of choice in early aircraft engines. Its use necessitated the teardown of engines every 25 hours or so to remove the varnish that was formed by the engines heat. Fortunately petroleum based lubricants arrived on the scene in the 1920's.

  10. #10
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Redhot Jumper Caster Oil Uses.............................



    CASTOR OIL: MODERN USES FOR AN OLD FOLK REMEDY

    "by Simone Gabbay."


    http://www.annieappleseedproject.org/castoroiluses.html



    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  11. #11
    Master OptiBoarder
    Join Date
    Oct 2005
    Location
    new york
    Occupation
    Optometrist
    Posts
    3,749
    Not sure what all the excitement is about...

    Castor oil is a lubricant...agreed. Castor oil aids in lubricating the eye and keeping the cornea from suffering the effects of Dry Eye Syndrome... agreed.

    But the Castor Oil preparations cited in the articles, unlike other dry eye preparations, must be kept at 4 degrees centigrade...which means that patients on the go must carry around a small refrigerator with them.

    Also, the articles indicate that the Castor oil preparations are .125% of this...and homogonized with that...and emulsified with polyoxywhatchamacalit ... What Dry Eye sufferer is gonna do that?

    If the excitement is over the fact that Castor Oil is cheap, you can be sure that if a pharmaceutical company figured out a way to make it a viable product, it would be expensive.

    If Castor oil cured the disease, it might be worth it...but it doesn't.

  12. #12
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Redhot Jumper Wikipedia on Castor Oil

    Castor oil

    From Wikipedia, the free encyclopedia


    Jump to: navigation, search
    Castor oil is a vegetable oil obtained from the castor bean (technically castor seed as the castor plant, Ricinus communis, is not a member of the bean family). Castor oil (CAS number 8001-79-4) is a colorless to very pale yellow liquid with mild or no odor or taste. Its boiling point is 313 C (595 F) and its density is 961 kgm-3.[1] It is a triglyceride in which approximately ninety percent of fatty acid chains are ricinoleic acid. Oleic and linoleic acids are the other significant components.[2]
    The structure of the major component of castor oil is shown below:


    Ricinoleic acid, a monounsaturated, 18-carbon fatty acid, is unusual in that it has a hydroxyl functional group on the twelfth carbon. This functional group causes ricinoleic acid (and castor oil) to be unusually polar, and also allows chemical derivatization that is not practical with most other seed oils. It is the hydroxyl group which makes castor oil and ricinoleic acid valuable as chemical feedstocks. Compared to other seed oils which lack the hydroxyl group, castor oil demands a higher price. As an example, in July 2007 Indian castor oil sold for about US$0.90 per kilogram (US$0.41 per pound)[3] while US soybean, sunflower and canola oil sold for about US$0.30 per kilogram (US$0.14 per pound)[4]
    Castor oil and its derivatives have applications in the manufacturing of soaps, lubricants, hydraulic and brake fluids, paints, dyes, coatings, inks, cold resistant plastics, waxes and polishes, nylon, pharmaceuticals and perfumes.
    Sulfonated castor oil, also called Sulfonated (sulfated) castor oil, or Turkey Red Oil, is the only oil that completely disperses in water. It is made by adding sulfuric acid to pure castor oil[5]. This allows easy use for making bath oil products. It was the first synthetic detergent after ordinary soap. It is used in formulating lubricants, softeners, and dyeing assistants[6].
    The castor seed contains ricin, a toxic protein removed by cold pressing and filtering.[7] However, harvesting castor beans is not without risk, [8] Allergenic compounds found on the plant surface can cause permanent nerve damage, making the harvest of castor beans a human health risk. India, Brazil and China are the major crop producers and the workers suffer harmful side effects from working with these plants.[9] These health issues, in addition to concerns about the toxic byproduct (ricin) from castor oil production, have encouraged the quest for alternative, domestic sources for hydroxy fatty acids.[10][11] Alternatively, some researchers are trying to genetically modify the castor plant to prevent the synthesis of ricin.[12]

    http://en.wikipedia.org/wiki/Castor_oil#Background
    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  13. #13
    Banned
    Join Date
    Jun 2000
    Location
    Only City in the World built over a Volcano
    Occupation
    Dispensing Optician
    Posts
    12,996
    The excitement isn't over the fact that Castor Oil is cheap, the excitement is over the fact it works with no negative side effects.
    This cannot be said for any preserved Rx-able substance (most of which work only from the exam chair to the car). It does not have allergic reactions, lower the immune system, etc.

    Can't say I am excited over something I have known about since about '64, and has been in use since the early '50's. But I am very disappointed in a "medical" disipline that will Rx expensive "cures" that don't work vs. those that do.

    As to the "busy on the go population" usually one drop per eye upon retireing is adequate. Usually it does not only serve as a "lubricant" but also as an eventual cure.

    Chip

  14. #14
    Master OptiBoarder
    Join Date
    Apr 2006
    Location
    NA
    Occupation
    Dispensing Optician
    Posts
    1,255
    Buy Chip Anderson's Caster Oil, Guaranteed to improve your TBUT! A $10000 value available to you today for only ten easy payments of $29.99! LOL

  15. #15
    Master OptiBoarder
    Join Date
    Oct 2005
    Location
    new york
    Occupation
    Optometrist
    Posts
    3,749
    Quote Originally Posted by EyeFitWell View Post
    Buy Chip Anderson's Caster Oil, Guaranteed to improve your TBUT! A $10000 value available to you today for only ten easy payments of $29.99! LOL
    I see...is that one tablespoon per day in the eye, or by mouth?

  16. #16
    Master OptiBoarder
    Join Date
    Oct 2005
    Location
    new york
    Occupation
    Optometrist
    Posts
    3,749
    Quote Originally Posted by chip anderson View Post
    ... Usually it does not only serve as a "lubricant" but also as an eventual cure.

    Chip
    Wow. That's good to know. Could you post the ophthalmological articles which document this?

  17. #17
    OptiBoardaholic
    Join Date
    May 2000
    Location
    B.C. Canada
    Occupation
    Dispensing Optician
    Posts
    1,189
    It works! I just downed a whole cupfull of castor oil, and boy did my eyes water.
    Um, I meant elicited a bi-lateral lacrimal hypersecretion.

  18. #18
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Redhot Jumper No dry eye cure...............

    Quote Originally Posted by Dave Nelson View Post
    It works! I just downed a whole cupfull of castor oil, and boy did my eyes water.
    Um, I meant elicited a bi-lateral lacrimal hypersecretion.
    Actually if you would have actually downed a cup full of Castor oil you would had no bi-lateral lacrimal hypersecretion but would have induced a severe diarrhea, and no dry eye cure.=============you would have been wet on an other part of your body.
    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  19. #19
    Manuf. Lens Surface Treatments
    Join Date
    Aug 2002
    Location
    in Naples FL for the Winter months
    Occupation
    Other Optical Manufacturer or Vendor
    Posts
    23,240

    Redhot Jumper

    Quote Originally Posted by fjpod View Post
    Wow. That's good to know. Could you post the ophthalmological articles which document this?

    <LI class=g>ScienceDirect - Ophthalmology : Low-concentration homogenized ...

    Low-concentration homogenized castor oil eye drops for noninflamed obstructive ... 1 Department of Ophthalmology, Tokyo Dental College, Chiba, Japan ...
    linkinghub.elsevier.com/retrieve/pii/S0161642002012629 - Similar pages - Note this
    by E Goto - 2002 - Cited by 20 - Related articles - All 5 versions
    <LI class=g>
    <LI class=g>Ophthalmology - Low-concentration homogenized castor oil eye drops ...Ophthalmology, Volume 109, Issue 11, Pages 2030-2035, November 2002, Authors:Eiki Goto; Jun Shimazaki; Yu Monden; Yoji Takano; Yukiko Yagi; Shigeto Shimmura ...
    www.ophsource.org/periodicals/ophtha/article/S0161-6420(02)01262-9/abstract - 41k - Cached - Similar pages - Note this


    <LI class=g style="MARGIN-LEFT: 3em">Ophthalmology

    SEARCH OPHTHALMOLOGY. VIDEO COLLECTION. ART GALLERY. EDITORSHIP SERIES ... Contact dermatitis from castor oil in zinc and castor oil cream. ...
    www.ophsource.org/periodicals/ophtha/medline/related/MDLN.6627931 - 64k - Cached - Similar pages - Note this
    More results from www.ophsource.org
    <LI class=g style="MARGIN-LEFT: 3em">
    <LI class=g>Low-concentration homogenized castor oil eye drops ...

    <LI class=g>Department of Ophthalmology, Tokyo Dental College, Chiba, Japan. OBJECTIVE: We developed low-concentration homogenized castor oil eye drops for the ...
    www.ncbi.nlm.nih.gov/pubmed/12414410 - Similar pages - Note this
    by E Goto - 2002 -
    Cited by 20 - Related articles - All 5 versions


    <LI class=g>Low-concentration homogenized castor oil eye drops for noninflamed ...

    (2) Department of Ophthalmology, Keio University School of Medicine, Tokyo, JAPON ... Methods: After a preliminary study of eye drops containing castor oil, ...
    cat.inist.fr/?aModele=afficheN&cpsidt=14361189 - Similar pages - Note this
    by E GOTO - 2002 - Cited by 20 - Related articles - All 5 versions
    <LI class=g>
    <LI class=g>Castor oil drops safely treat meibomian gland dysfunction ...

    Chiba, Japan -- Low-concentration homogenized castor oil eye drops seem to ... his co-authors of a study published in Ophthalmology (2002;109:2030- 2035). ...
    www.accessmylibrary.com/coms2/summary_0286-31094236_ITM - 25k - Cached - Similar pages - Note this
    <LI class=g>Polyethoxylated castor oil products as anti-inflammatory agents ...

    Polyethoxylated castor oil products as anti-inflammatory agents - US Patent ... into the Rat Food Pad, Investigative Ophthalmology and Visual Science, vol. ...
    www.patentstorm.us/patents/5686488.html - Similar pages - Note this
    by JC Nixon - 1997 - Related articles
    <LI class=g>
    <LI class=g>Benefits and Side Effects of Different Vegetable Oil Vectors on ...

    2007 by The Association for Research in Vision and Ophthalmology, Inc. ... The results demonstrated that castor oil exerts cytotoxic effects on conjunctival ...
    www.iovs.org/cgi/content/abstract/48/11/5000 - Similar pages - Note this
    by T Said - 2007 - Related articles - All 2 versions
    <LI class=g>Opthalmic composition - Patent 4879294

    Opthalmic composition. Document Type and Number: ... palm kernel oil, castor oil, sunflower seed oil, wall flower oil, sesame oil; or mineral oils. ...
    www.freepatentsonline.com/4879294.html - Similar pages - Note this
    by RD Schoenwald - 1989 - Cited by 1 - Related articles - All 2 versions
    <LI class=g>castor oil Infoplease.com

    Castor oil drops safely treat meibomian gland dysfunction (Ophthalmology Times). Search HighBeam Research for:. Additional search results provided by ...
    www.infoplease
    Chris Ryser
    ________________________________________
    DLO. NA.IC.I.T.PO

    http://optochemicals.com............................. http://arcoatings.com

  20. #20
    Master OptiBoarder
    Join Date
    Oct 2005
    Location
    new york
    Occupation
    Optometrist
    Posts
    3,749
    Thanks for the references...

    Virtually all of them refer to a single study. The study doesn't seem to claim a "cure" for dry eye, but it does imply amelioration with ongoing use.

    A controlled comparison study with other forms of dry eye treatment would be interesting.

    ...but I don't know about increasing our imports of foreign oil??
    http://www.highbeam.com/doc/1G1-97629542.html

  21. #21
    Banned
    Join Date
    Jun 2000
    Location
    Only City in the World built over a Volcano
    Occupation
    Dispensing Optician
    Posts
    12,996
    Hang in there Fidg... I got it here somewhere and I have more coming from some friends. But if you are impatient for proof dear Pontias you might google Girard, L.G. and I am sure that have enough to convince even Thomas. Or if you have to have "the truth from the horse's mouth, I have Louis Girard, M.D.'s phone number and you can call him.

    Don't know who Louis Girard, M.D. is/was? Pity....


    Chip

  22. #22
    Underemployed Genius Jacqui's Avatar
    Join Date
    Oct 2003
    Location
    Frostbite Falls, Mn.
    Occupation
    Optical Wholesale Lab (other positions)
    Posts
    7,417
    You might also want to dig through the studies done by the Mayo Clinic, there should be something there.
    Proud Member of the ABE Club!
    Don't feed the Beast...

  23. #23
    Master OptiBoarder
    Join Date
    Oct 2005
    Location
    new york
    Occupation
    Optometrist
    Posts
    3,749
    Quote Originally Posted by chip anderson View Post
    Hang in there Fidg... I got it here somewhere and I have more coming from some friends. But if you are impatient...
    Chip
    Cherp,
    I'm in no hurry.
    fjdop

  24. #24
    OptiBoard Novice
    Join Date
    May 2019
    Location
    USA
    Occupation
    Ophthalmologist
    Posts
    1
    When applying castor oil to your eyelashes, be very careful that it doesn't get into your eye. In the event that it does, flush your eye with water. Castor oil is generally regarded as safe. However, some people may have an allergic reaction to castor oil.

  25. #25
    OptiWizard
    Join Date
    Feb 2016
    Location
    usa
    Occupation
    Dispensing Optician
    Posts
    316
    When using an internet forum be very careful that you don't dig up 11 year old threads. It is generally considered very poor form.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Similar Threads

  1. Replies: 0
    Last Post: 05-24-2006, 06:34 PM
  2. old stuff
    By OPTIDONN in forum Optical Marketplace
    Replies: 0
    Last Post: 03-06-2005, 05:12 PM
  3. Need some stuff!
    By LENNY in forum Optical Marketplace
    Replies: 1
    Last Post: 05-18-2001, 11:49 AM
  4. sold my stuff now looking for stuff
    By Jeff Trail in forum Optical Marketplace
    Replies: 0
    Last Post: 02-14-2001, 05:58 PM
  5. Stuff
    By chip anderson in forum Optical Marketplace
    Replies: 1
    Last Post: 02-05-2001, 11:55 AM

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
OptiBoard is proudly sponsored by:
Younger Optics and Vision Equipment