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Thread: Sideeffects from flourescein strips?

  1. #1
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    Arrow Sideeffects from flourescein strips?

    Have You ever experienced any side effects when using flourescein strips when looking for corneal or conjunctival staining?
    Or have you ever heard of any side effects?
    Should we warn costomers of evetuel side effects??

  2. #2
    What's up? drk's Avatar
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    Mild stinging, discolored eyelids and mucus, potential staining of clothes.

    None of these are serious, nor rise to the level of "prior consent needed".

    I just use it with impunity with zero complaints.

  3. #3
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    Even those side effects listed are often caused by paper fibres coming off the strip. The stuff is routinely injected right into the bloodstream.

  4. #4
    OptiBoard Professional Ory's Avatar
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    Fluorescein Sodium

    U.S. Brand Names AK-Fluor; Fluorescite®; Fluorets® Ophthalmic Strips; Fluor-I-Strip®; Fluor-I-Strip-AT®; Fluress®; Ful-Glo® Ophthalmic Strips; Ophthifluor®

    Synonyms Soluble Fluorescein

    Use Demonstrates defects of corneal epithelium; diagnostic aid in ophthalmic angiography

    Pregnancy Risk Factor C (topical); X (parenteral)

    Contraindications Hypersensitivity to fluorescein or any other component of the formulation; do not use with soft contact lenses, as this will cause them to discolor; pregnancy (parenteral product)

    Warnings/Precautions Use with caution in patients with history of hypersensitivity, allergies, or asthma; avoid extravasation; should not be used in patients with soft contact lenses, will cause them to discolor

    Adverse Reactions
    1% to 10%:
    Dermatologic: Burning sensation
    Local: Temporary stinging
    <1%: Syncope, hypotension, cardiac arrest, basilar artery ischemia, severe shock, headache, nausea, GI distress, vomiting, thrombophlebitis

    Dosage
    Ophthalmic:
    Solution: Instill 1-2 drops of 2% solution and allow a few seconds for staining; wash out excess with sterile water or irrigating solution
    Strips: Moisten strip with sterile water. Place moistened strip at the fornix into the lower cul-de-sac close to the punctum. For best results, patient should close lid tightly over strip until desired amount of staining is obtained. Patient should blink several times after application.
    Removal of foreign bodies, sutures or tonometry (Fluress®): Instill 1 or 2 drops (single instillations) into each eye before operating
    Deep ophthalmic anesthesia (Fluress®): Instill 2 drops into each eye every 90 seconds up to 3 doses
    Injection: Prior to use, perform intradermal skin test; have epinephrine 1:1000, an antihistamine, and oxygen available
    Children: 3.5 mg/lb (7.5 mg/kg) injected rapidly into antecubital vein
    Adults: 500-750 mg injected rapidly into antecubital vein

    Dosage Forms
    Injection (AK-Fluor, Fluorescite®, Ophthifluor®): 10% [100 mg/mL] (5 mL); 25% [250 mg/mL] (2 mL, 3 mL)
    Solution, ophthalmic: 2% [20 mg/mL] (1 mL, 2 mL, 15 mL)
    Fluress®: 0.25% [2.5 mg/mL] (5 mL) [contains benoxinate 0.4%]
    Strip, ophthalmic:
    Fluorets®, Fluor-I-Strip-AT®: 1 mg
    Fluor-I-Strip®: 9 mg
    Ful-Glo®: 0.6 mg

  5. #5
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    The reason I ask is that I have a costomer who blames me for not warning him of side effects. Claims it caused him to get at fever - sounds unlikely to me!

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